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1

Alternatives to animal testing: current status and future perspectives

Manfred Liebsch, Barbara Grune, Andrea Seiler, Daniel Butzke, Michael Oelgeschläger, Ralph Pirow, Sarah Adler, Christian Riebeling, Andreas Luch

Journal:

Archives of Toxicology

Year:

2011

Language:

english

File:

PDF, 811 KB

english, 2011

2

Validation of the 3D Skin Comet assay using full thickness skin models: Transferability and reproducibility

Reisinger, Kerstin, Blatz, Veronika, Brinkmann, Joep, Downs, Thomas R., Fischer, Anja, Henkler, Frank, Hoffmann, Sebastian, Krul, Cyrille, Liebsch, Manfred, Luch, Andreas, Pirow, Ralph, Reus, Astrid A

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2018

Language:

english

File:

PDF, 822 KB

english, 2018

3

Estrogen and Progestogen Correlates of the Structure of Female Copulation Calls in Semi-Free-Ranging Barbary Macaques (Macaca sylvanus)

Dana Pfefferle, Michael Heistermann, Ralph Pirow, J. Keith Hodges, Julia Fischer

Journal:

International Journal of Primatology

Year:

2011

Language:

english

File:

PDF, 251 KB

english, 2011

4

Acclimatory responses of theDaphnia pulexproteome to environmental changes. II. Chronic exposure to different temperatures (10 and 20°C) mainly affects protein metabolism

Susanne Schwerin, Bettina Zeis, Tobias Lamkemeyer, Rüdiger J Paul, Marita Koch, Johannes Madlung, Claudia Fladerer, Ralph Pirow

Journal:

Year:

2009

Language:

english

File:

PDF, 2.29 MB

english, 2009

5

Physiological responses ofDaphnia pulexto acid stress

Anna K Weber, Ralph Pirow

Journal:

Year:

2009

Language:

english

File:

PDF, 1.56 MB

english, 2009

6

Acclimatory responses of theDaphnia pulexproteome to environmental changes. I. Chronic exposure to hypoxia affects the oxygen transport system and carbohydrate metabolism

Bettina Zeis, Tobias Lamkemeyer, Rüdiger J Paul, Frank Nunes, Susanne Schwerin, Marita Koch, Wolfgang Schütz, Johannes Madlung, Claudia Fladerer, Ralph Pirow

Journal:

Year:

2009

Language:

english

File:

PDF, 1.54 MB

english, 2009

7

Epipodite and fat cells as sites of hemoglobin synthesis in the branchiopod crustaceanDaphnia magna

Torsten Goldmann, Bertram Becher, Klaus H. Wiedorn, Ralph Pirow, Michael E. Deutschbein, Ekkehard Vollmer, Rüdiger J. Paul

Journal:

Histochemistry and Cell Biology

Year:

1999

Language:

english

File:

PDF, 322 KB

english, 1999

8

Developmental toxicity testing in the 21st century: the sword of Damocles shattered by embryonic stem cell assays?

Andrea Seiler, Michael Oelgeschläger, Manfred Liebsch, Ralph Pirow, Christian Riebeling, Tewes Tralau, Andreas Luch

Journal:

Archives of Toxicology

Year:

2011

Language:

english

File:

PDF, 2.14 MB

english, 2011

9

Cationic composition and acid–base state of the extracellular fluid, and specific buffer value of hemoglobin from the branchiopod crustaceanTriops cancriformis

Ralph Pirow, Ina Buchen, Marc Richter, Carsten Allmer, Frank Nunes, Andreas Günsel, Wiebke Heikens, Tobias Lamkemeyer, Björn M. von Reumont, Stefan K. Hetz

Journal:

Journal of Comparative Physiology B

Year:

2009

Language:

english

File:

PDF, 629 KB

english, 2009

10

Temporal environmental change, clonal physiology and the genetic structure of a Daphnia assemblage (D. galeata–hyalina hybrid species complex)

OLAF PINKHAUS, SUSANNE SCHWERIN, RALPH PIROW, BETTINA ZEIS, INA BUCHEN, ULRIKE GIGENGACK, MARITA KOCH, WOLFGANG HORN, RÜDIGER J. PAUL

Journal:

Freshwater Biology

Year:

2007

Language:

english

File:

PDF, 450 KB

english, 2007

11

Post-Conflict Affiliation in Barbary Macaques is Influenced by Conflict Characteristics and Relationship Quality, but Does Not Diminish Short-Term Renewed Aggression

Annika Patzelt, Ralph Pirow, Julia Fischer

Journal:

Year:

2009

Language:

english

File:

PDF, 211 KB

english, 2009

12

Facial expressions modulate the ontogenetic trajectory of gaze-following among monkeys

Christoph Teufel, Anke Gutmann, Ralph Pirow, Julia Fischer

Journal:

Developmental Science

Year:

2010

Language:

english

File:

PDF, 626 KB

english, 2010

13

Native and subunit molecular mass and quarternary structure of the hemoglobin from the primitive branchiopod crustacean Triops cancriformis

Morgane Rousselot, Elmar Jaenicke, Tobias Lamkemeyer, J. Robin Harris, Ralph Pirow

Journal:

Year:

2006

Language:

english

File:

PDF, 1.70 MB

english, 2006

14

Oxygen binding and its allosteric control in hemoglobin of the primitive branchiopod crustacean Triops cancriformis

Ralph Pirow, Nadja Hellmann, Roy E. Weber

Journal:

Year:

2007

Language:

english

File:

PDF, 1.43 MB

english, 2007

15

Water fleas (Daphnia magna) provide a separate ventilatory mechanism for their brood

Matthias D. Seidl, Ralph Pirow, Rüdiger J. Paul

Journal:

Year:

2002

Language:

english

File:

PDF, 1.44 MB

english, 2002

16

Arenicola marina extracellular hemoglobin: a new promising blood substitute

Morgane Rousselot, Eric Delpy, Christophe Drieu La Rochelle, Vincent Lagente, Ralph Pirow, Jean-François Rees, Agnès Hagege, Dominique Le Guen, Stéphane Hourdez, Franck Zal

Journal:

Biotechnology Journal

Year:

2006

Language:

english

File:

PDF, 568 KB

english, 2006

17

Development of heart rate responses to acoustic stimuli in Muscovy duck embryos

Joachim Höchel, Ralph Pirow, Martin Nichelmann

Journal:

Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology

Year:

2002

Language:

english

File:

PDF, 1.08 MB

english, 2002

18

Systemic and metabolic responses in Daphnia magna to anoxia

Rüdiger J. Paul, Michael Colmorgen, Ralph Pirow, Yi-Horn Chen, Ming-Cheng Tsai

Journal:

Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology

Year:

1998

Language:

english

File:

PDF, 690 KB

english, 1998

19

Development of heart rate rhythmicity in Muscovy duck embryos

Joachim Höchel, Elmar Mohr, Martin Nichelmann, Ralph Pirow, Hiroshi Tazawa

Journal:

Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology

Year:

1999

Language:

english

File:

PDF, 306 KB

english, 1999

20

A method for noninvasive, long-term recording of the avian embryo heart rate

Ralph Pirow, Rainer Bilsing, Martin Nichelmann, Joachim Höchel

Journal:

Physiology & Behavior

Year:

1995

Language:

english

File:

PDF, 370 KB

english, 1995

21

The process of hypoxic induction of Daphnia magna hemoglobin: subunit composition and functional properties

Bettina Zeis, Bertram Becher, Tobias Lamkemeyer, Silke Rolf, Ralph Pirow, Rüdiger Jörg Paul

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

2003

Language:

english

File:

PDF, 689 KB

english, 2003

22

The DNT-EST: A predictive embryonic stem cell-based assay for developmental neurotoxicity testing in vitro

Hayess, Katrin, Riebeling, Christian, Pirow, Ralph, Steinfath, Matthias, Sittner, Dana, Slawik, Birgitta, Luch, Andreas, Seiler, Andrea E.M.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.38 MB

english, 2013

23

Statistical analysis of the hen's egg test for micronucleus induction (HET-MN assay)

Hothorn, Ludwig A., Reisinger, Kerstin, Wolf, Thorsten, Poth, Albrecht, Fieblinger, Dagmar, Liebsch, Manfred, Pirow, Ralph

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2013

Language:

english

File:

PDF, 939 KB

english, 2013

24

Wind of Change Challenges Toxicological Regulators

Tewes Tralau, Christian Riebeling, Ralph Pirow, Michael Oelgeschläger, Andrea Seiler, Manfred Liebsch and Andreas Luch

Journal:

Environmental Health Perspectives

Year:

2012

Language:

english

File:

PDF, 6.39 MB

english, 2012

25

EFSA's draft risk assessments of bisphenol A (BPA), the increasing role of uncertainty

Husøy, Trine, Hart, Andrew D., Pirow, Ralph, Pocas, Maria de Fatima T., Mennes, Wim C., Wölfle, Detlef, Arcella, Davide, Theobald, Anne, Croera, Cristina, Castoldi, Anna F.

Journal:

Toxicology Letters

Year:

2014

Language:

english

File:

PDF, 56 KB

english, 2014

26

Sequencing of Hemoglobin Gene 4 ( dmhb4 ) and Southern Blot Analysis Provide Evidence of More Than Four Members of the Daphnia magna Globin Family

NUNES, Frank, SPIERING, Désirée, WOLF, Marc, WENDLER, Alexandra, PIROW, Ralph, PAUL, Rüdiger J.

Journal:

Bioscience Biotechnology and Biochemistry

Year:

2005

Language:

english

File:

PDF, 319 KB

english, 2005

27

Safety limits for elements in toys: a comparison between the old and the new European toys safety directive

Vieth, Bärbel, Pirow, Ralph, Luch, Andreas

Journal:

Archives of Toxicology

Year:

2014

Language:

english

File:

PDF, 178 KB

english, 2014

28

Wind of Change Challenges Toxicological Regulators

Tralau, Tewes, Riebeling, Christian, Pirow, Ralph, Oelgeschläger, Michael, Seiler, Andrea, Liebsch, Manfred, Luch, Andreas

Journal:

Environmental Health Perspectives

Year:

2012

Language:

english

File:

PDF, 542 KB

english, 2012

29

Respiratory Adaptations to Running‐Water Microhabitats in Mayfly LarvaeEpeorus sylvicolaandEcdyonurus torrentis, Ephemeroptera

Christopher Bäumer, Ralph Pirow, and Rüdiger J. Paul

Journal:

Physiological and Biochemical Zoology

Year:

2000

Language:

english

File:

PDF, 226 KB

english, 2000

30

Characterization of chemical-induced sterile inflammation in vitro: application of the model compound ketoconazole in a human hepatic co-culture system

Wewering, Franziska, Jouy, Florent, Wissenbach, Dirk K., Gebauer, Scarlett, Blüher, Matthias, Gebhardt, Rolf, Pirow, Ralph, von Bergen, Martin, Kalkhof, Stefan, Luch, Andreas, Zellmer, Sebastian

Journal:

Archives of Toxicology

Year:

2017

Language:

english

File:

PDF, 956 KB

english, 2017

31

Seasonal and interannual changes in water temperature affect the genetic structure of a Daphnia assemblage ( D. longispina complex) through genotype-specific thermal tolerances

Paul, Rüdiger J., Mertenskötter, Ansgar, Pinkhaus, Olaf, Pirow, Ralph, Gigengack, Ulrike, Buchen, Ina, Koch, Marita, Horn, Wolfgang, Zeis, Bettina

Journal:

Limnology and Oceanography

Year:

2012

Language:

english

File:

PDF, 3.33 MB

english, 2012

32

Encoding Conditions Affect Recognition of Vocally Expressed Emotions Across Cultures

Jürgens, Rebecca, Drolet, Matthis, Pirow, Ralph, Scheiner, Elisabeth, Fischer, Julia

Journal:

Frontiers in Psychology

Year:

2013

Language:

english

File:

PDF, 1.39 MB

english, 2013

33

Validation of the 3D reconstructed human skin Comet assay, an animal-free alternative for following-up positive results from standard in vitro genotoxicity assays

Pfuhler, Stefan, Pirow, Ralph, Downs, Thomas R, Haase, Andrea, Hewitt, Nicola, Luch, Andreas, Merkel, Marion, Petrick, Claudia, Said, AndrÃ©, SchÃ¤fer-Korting, Monika, Reisinger, Kerstin

Journal:

Year:

2020

File:

PDF, 563 KB

2020

34

Response to the letter to the editor from Carrillo and Danneels

Pirow, Ralph, Hellwig, Nicole, Huhse, Bettina, Hutzler, Christoph, Luch, Andreas

Journal:

Critical Reviews in Toxicology

Year:

2020

File:

PDF, 591 KB

2020

35

Use compatibility intervals in regulatory toxicology

Hothorn, Ludwig A., Ralph Pirow,

Journal:

Regulatory Toxicology and Pharmacology

Year:

2020

File:

PDF, 707 KB

2020

36

Pharmacokinetics of bisphenol A in humans following dermal administration

Sasso, Alan F., Pirow, Ralph, Andra, Syam S., Church, Rebecca, Nachman, Rebecca M., Linke, Susanne, Kapraun, Dustin F., Schurman, Shepherd H., Arora, Manish, Thayer, Kristina A., Bucher, John R., Birn

Journal:

Environment International

Year:

2020

File:

PDF, 1.13 MB

2020

37

A scientific review of colorful textiles

Nicolai, Suna, Tralau, Tewes, Luch, Andreas, Pirow, Ralph

Journal:

Journal für Verbraucherschutz und Lebensmittelsicherheit

Year:

2020

File:

PDF, 818 KB

2020